Profluent Bio

Profluent is an AI-powered research platform that offers protein design, enabling breakthroughs in medicine, agriculture, and sustainability by creating novel, functional proteins with advanced generative models.

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Updated 09/24/2025
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What is Profluent?

  • Founder: Ali Madani (Co-founder & CEO), Alexander Meeske (Co-founder)
  • Launch: 2022
  • Use Cases: Therapeutic protein design, antibody generation, gene editing tools, industrial enzymes, agricultural applications, sustainable biotechnology solutions
  • Technology: Generative protein language models, deep learning, large-scale biological datasets, wet-lab validation, structural and functional protein design

Profluent is an AI-powered research platform exploring the use of generative AI technologies to create new proteins with unique functions. Still, Profluent's technology does more than just build proteins by natural evolution and incremental alterations; it also explores the large protein sequence space to create molecules specially tailored for desired function. Profluent's platform features ProGen3, advanced protein language models that can create complete proteins (like antibodies and modified parts), along with OpenCRISPR, an AI-designed gene editor that shows the company's skill in making small, effective tools for editing genomes. Profluent can show that its protein designs work in real-life uses in medicine, farming, and industry by mixing new deep learning methods with proven lab techniques. Profluent combines AI technology with real-world testing, making it a leader in the new wave of protein engineering that addresses challenges in health, sustainability, and biotechnology.

 

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Frequently Asked Questions

Profluent designs proteins using generative AI, enabling the creation of entirely new molecules instead of relying on naturally occurring variations or stepwise modifications.

ProGen3 is Profluent’s advanced model that understands protein language, trained on billions of protein sequences, and can create and improve functional proteins for various uses.

OpenCRISPR is an AI-designed gene editor developed by Profluent, offering compact, efficient, and versatile genome editing capabilities for therapeutic and research purposes.

Industries such as healthcare, agriculture, pharmaceuticals, and biotechnology can leverage Profluent’s protein design to develop therapies, sustainable solutions, and industrial enzymes.

Yes. All AI-generated protein designs undergo laboratory validation to confirm function, performance, and applicability in real-world biological environments.
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